Division of Animal Anatomy
Prof. dr hab. Maciej Janeczek,
Dr hab. Aleksander Chrószcz, prof. uczelni
Scientific profile
Archaeozoology and paleopathology, in vivo investigation on animal models. Cooperation with: Institute of Archaeology, University of Wroclaw; Institute of Archaeozology and Ethnology of the Polish Academy of Sciences; Institute of Archaeology Slovak Academy of Sciences, Nitra, Slovakia; Department of Animal Anatomy, University of Warmia and Mazury, Olsztyn; Department of Experimental Surgery and Biomaterial Research, Wroclaw Medical University; Department of Anatomy, Istanbul University, Turkey.
Halina Purzyc, DVM, PhD
Halina Purzyc is a veterinary doctor. At the University, she teaches the animal anatomy. The topics of her research include morphology and morphometry of horses. She focuses also on the veterinary neuroanatomy and anatomy of laboratory animals – especially of its vascular system. She cooperates with Warsaw University of Life Sciences – SGGW and
University of Veterinary Medicine and Pharmacy in Košice.
Joanna Klećkowska-Nawrot, DVM, PhD
Karolina Goździewska-Harłajczuk, DVM, PhD
Scientific profile: Morphology and development of the organum visus and selected organs of the digestive system (organum gustatorium and stomach) and lymphatic system (HALT, GALT) in reptiles, birds, and mammals. We used histological, histochemical, immunohistochemical and ultrastructural methods (TEM, SEM).
Cooperation with: Wroclaw Zoological Garden; Electron Microscopy Laboratory (Wroclaw University of Environmental and Life Sciences); Museum of Natural History (Wroclaw University of Environmental and Life Sciences); Transmission Electron Microscopy Laboratory (University of Wroclaw); Institute of Animal Breeding (Wroclaw University of Environmental and Life Sciences); Department of Morphological Sciences (Warsaw University of Life Sciences-SGGW); Institute of Psychology (Polish Academy of Sciences, Warsaw); Department of Poultry Diseases, National Veterinary Research Institute, Puławy.
Renata Nowaczyk, DVM, PhD
Reproductive immunology in the canine species, interactions between the immune system and endocrine system, involvement of the immune system in endocrine regulation. The molecular aspects of the reproductive endocrinology and immunology. Studies conducted on tissue samples and cell lines using immunohistochemistry and molecular biology techniques. Cooperation with: Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, Switzerland.
Edyta Pasicka, PhD
Scientific profile: author of scientific papers on the anatomy of domesticated and wild living animals, breeding and usage of horses, structure of movement apparatus and functional morphometry. Also craniometric, osteometric, odontometric and genetic studies in the Equidae family spectrum, taphonomy and osteology of their fossil representatives, as well as archaeozoology and paleopathology. Scientific cooperation: Natural Resources Institute Finland (Luke), Finland. Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Finland. Department of Anatomy, Osteoarchaeology Lab, Faculty of Veterinary Medicine, Istanbul University, Turkey. The Royal (Dick) School of Veterinary Studies and The Roslin Institute, The University of Edinburgh, Easter Bush Veterinary Campus, Midlothian, Scotland. Department of Animal Anatomy, Faculty of Veterinary Medicine, NULES, Kiev, Ukraine. National Museum of Natural History, National Academy of Sciences of Ukraine, Kiev, Ukraine.
Dominik Poradowski, DVM, PhD
- effect of combinations between non-steroidal anti-inflammatory drugs, cytostatic drugs and bisphosphonates on viability, cell cycle and apoptosis of cells derived from canine (D-17) and human (U-2 OS) osteosarcoma cell lines,
- comparison of expression of cell markers i.e. COX-2, mPGES-1 or osteocalcin in cell of spontaneous osteosarcomas collected from dogs and humans and in cell derived from established cell lines,
- trial of establishing primary cell lines from stroma of mitral and aortic valves of pig,
- evaluation of expression level of TGF-ß, collagen III, elastin, MMP-2 in cells of stroma of mitral and aortic valves of pig,
- effect of angiotensin II, benazepril, cirazolin and caffeine on cells of stroma of mitral and aortic valves of pig.
Cooperation with CEU Cardinal Herrera University.
Division of Animal Physiology
Division of Histology and Embryology
The Department conducts research in cooperation with other scientific centers in the field of histophysiology of organs and tissues. They concern mainly hard tissues such as bone and cartilage tissue and tooth tissues in various experimental systems of both contemporary and fossil material. In addition, research which investigate various aspects of changes in organs, both in the biological and in the veterinary sciences. Histological and smear specimens in routine staining and histochemical and immunohistochemical staining are performed. In addition, for a limited time, live cells derived from cell cultures and their response to various factors modulating their activity (mitochondria and cytoskeleton) are tested. The analyzes are performed using light and fluorescence microscopy along with a variety of morphometric tests assisted by Nis Elements AR software.
The effects of prebiotics and synbiotics on the histological structures of lymphatic organs in broilers. Team: Jan Madej, Marek Bednarczyk, Tadeusz Stefaniak
The condition of the immune system in chicken plays a significant role in the contemporary intensive poultry production. The ability of the immune system to respond to the environmental antigens, as well as efficacy of the immunisation, depends mainly on the level of development and condition of the system. Previous studies indicate that the type of intestinal microorganisms (microbiome) can influence the growth and health of their host (Fooks et al. 2002, Bednarczyk et al. 2011). Prebiotics and synbiotics (prebiotic + probiotic) influence the intestinal microbiome of the bird, can stimulate the gut-associated lymphoid tissue (GALT) and modulate the immune response of the host (Cesta 2006, Haghighi et al. 2006, 2008, Brisbin et al. 2011).
The study aimed to investigate the effects of in ovo-injected prebiotics and synbiotics on the histological structures and cell composition of lymphatic organs in broilers. Prebiotics and synbiotics, were injected into the egg: control group (C) –physiological saline; prebiotic 1 (Pre1) – inulin; prebiotic 2 (Pre2) – commercially developed, nondigestible transgalacto-oligosaccharide Bi2tos; synbiotic 1 (Syn1) – inulin + Lactococcus lactis subsp. lactis or synbiotic 2 (Syn2) – Bi2tos + L. lactis subsp. cremoris. The material for the study consist of thymus, bursa of Fabricius, spleen, distal end of ileum, and cecal tonsil taken from chickens on day 1, 7, 21, and 35 after hatching.
The results of this study indicate the immunomodulatory effect of pre- and synbiotics on the structure and cell composition of central and peripheral lymphatic organs of the chickens. Both the bioactives injected in ovo at day 12 of incubation had no adverse effect on the development of immune system in chickens. At day 7, after hatching, the decrease in B-cell number in BF was observed (Pre1, Pre2, and Syn2), as well as more pronounced colonisation of CT by T cells in all experimental groups and by B cells in both synbiotic-treated groups was also found. On day 21 Syn2 decreased the cortex/medulla ratio in the thymus, slowed the development of the cortex in bursal follicles and stimulated the B-dependent area in the spleen. At the same time both the synbiotics exerted more potent stimulatory effect on GALT colonisation by T cells than prebiotics alone. Similar effect in relation to B-cell number between the Syn2 and Pre2 groups was found.
(This research was carried out in cooperation with Department of Animal Biochemistry and Biotechnology, UTP University of Science and Technology, Bydgoszcz)
